Acidic Polysaccharide from <i>Angelica sinensis</i> Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-<i>κ</i>B Activation

<div>Effects of ASP treatment on iron homeostasis in ACD rats. (a) Prussian blue staining was performed on sections of formalin-fixed, paraffin-embedded spleens. (b) Serum ferritin levels were analyzed with a rat ferritin ELISA kit. (c) Serum iron and (d) spleen iron were measured spectrophotometrically. Immunoblots of protein expression of ferroportin and ferritin in the (e) spleens and (f) livers of ACD rats. <i>β</i>-Actin served as the loading control. One representative blot of 3 independent experiments is shown. 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Micrographs (magnification, 400x) are representative of one of three similar experiments and taken with Nikon Eclipse Ci.</div>

Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Acidic Polysaccharide from <i>Angelica sinensis</i> Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-<i>κ</i>B Activation 

Figure 6 | Acidic Polysaccharide from Angelica sinensis Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-κB Activation 