Research Article
Proinflammatory Cytokines Are Soluble Mediators Linked with Ventricular Arrhythmias and Contractile Dysfunction in a Rat Model of Metabolic Syndrome
Figure 3
Decreased response to physiological β-adrenergic stimulation in hearts from MS rats: Temporal responses to ISO stimulation (10 nM) for (a) normalized mechanical performance index (MPI), (b) maximum positive and (c) negative derivatives of left ventricular pressure (LVP), and (d) normalized oxygen consumption rate (MVO2). (e) Relationship between normalized MPI versus normalized MVO2. (Black, control group; white, MS group) versus control. Control group: ; MS group: .
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