Pitaya Extracts Induce Growth Inhibition and Proapoptotic Effects on Human Cell Lines of Breast Cancer via Downregulation of Estrogen Receptor Gene Expression

Figure 2

Formation of MCF-7 and MDA-MB-435 colonies. The number of MCF-7 and MDA-MB-435 colonies was determined after 18 days of culture in DMEM supplemented with 10% FCS containing PE at concentrations of 500 and 1000 μg/mL. Data are presented as mean ± standard deviation of 3 independent experiments, each performed at least in duplicate. indicates significant differences from the control group (; ).