Oxidative Medicine and Cellular Longevity / 2017 / Article / Fig 1

Review Article

P-glycoprotein (ABCB1) and Oxidative Stress: Focus on Alzheimer’s Disease

Figure 1

Proposed components of the Aβ efflux and influx across the blood-brain barrier. The two main Aβ efflux transporters include the low-density lipoprotein receptor-related protein 1 (LRP-1) and ABCB1, and the receptor for advanced glycation end-products (RAGE) is the main Aβ influx transporter.