Alleviation of Oxidative Damage and Involvement of Nrf2-ARE Pathway in Mesodopaminergic System and Hippocampus of Status Epilepticus Rats Pretreated by Intranasal Pentoxifylline

Table 3

Effects of pentoxifylline pretreatment on DA and its metabolites of status epilepticus rats.

	CON-cl	LICL-cl	PTX-in	PTX-ip	SE-cl	PTX.in-SE	PTX.ip-SE
CPu
DA (ng/g)
	5.3)	6.4)	6.4)	4.3)	9.1)	10.1)	10.3)
DOPAC (ng/g)
	5.7)	2.9)	6.0)	6.9)	7.8)	9.4)	6.9)
HVA (ng/g)
	5.7)	7.1)	8.4)	3.8)	10.2)	11.2)	6.5)
Hip
DA (ng/g)
	5.9)	7.4)	8.4)	10.5)	12.1)	8.5)	6.5)
DOPAC (ng/g)
	8.0)	5.8)	10.0)	6.1)	12.8)	7.5)	9.1)
HVA (ng/g)
	6.8)	5.9)	7.9)	6.8)	9.3)	5.1)	7.2)

CPu: caudate putamen; Hip: hippocampus; DA: dopamine; DOPAC: 3,4-dihydroxyphenylacetic acid; HVA: homovanillic acid. The value in brackets is the coefficient of variation.
and versus CON-cl; versus SE-cl.