Mulberry Anthocyanin Extract Ameliorates Oxidative Damage in HepG2 Cells and Prolongs the Lifespan of Caenorhabditis elegans through MAPK and Nrf2 Pathways

Figure 5

Effect of MAE on intracellular distribution of Nrf2, PGC-1α, and FOXO1 in HepG2 cells. The intensity of bands corresponding to Nrf2 in the nucleus was corrected by cytoplasmic protein levels to obtain relative measures of transcriptional activity among samples. FOXO1 expression level of the control in the cytoplasm is too low to be quantified. Vertical lines represent standard deviations of three replicates. Values with different letters above are significantly different, , one-way ANOVA test.