Research Article
Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury
Figure 2
Effect of XOI on ventricular function. (a) LVEDP, (b) maximal positive rate of the left ventricular pressure (+LVdP/dtmax), and (c) maximal negative rate of the left ventricular pressure (−LVdP/dtmax). IR + control: ischemia-reperfusion control; FEB10 + IR: febuxostat 10 mg/kg/day + ischemia-reperfusion; ALL100 + IR: allopurinol 100 mg/kg/day + ischemia-reperfusion. Data are expressed as the mean ± SEM; in each group. and versus sham; #, ##, and ### versus IR + control.
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