Research Article
Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury
Figure 6
Effect of XOI on (a1–d1) caspase-3 immunohistochemistry () (20x; scale bar 100 μm), (a2–d2) Bax immunohistochemistry () (20x; scale bar 100 μm), (a3–d3) Bcl-2 immunohistochemistry () (20x; scale bar 100 μm), and (a4–d4) TUNEL positivity (20x; scale bar 100 μm). (a) Sham; (b) IR + control: ischemia-reperfusion control; (c) FEB10 + IR: febuxostat 10 mg/kg/day + ischemia-reperfusion; (d) ALL100 + IR: allopurinol 100 mg/kg/day + ischemia-reperfusion.
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