Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury
Effect of XOI on MAPK protein expressions. (a) (A) p38 and p-p38 and (B) JNK and p-JNK; (b) (A) NFκBp65 and p-NFκBp65 and (B) ERK1/2 and p-ERK1/2. Protein expressions are normalized with β-actin. All the values are expressed as mean ± SEM; in each group. , , and versus IR + control; ### versus sham. a versus ALL100 + IR.
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