Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury

Table 1

Effect of XOI on histological scoring of cardiac tissue.

	Myonecrosis	Inflammatory cells	Edema
Sham	neg	neg	neg
IR-C	3+	3+	4+
FEB10 + IR	1+	1+	1+
ALL100 + IR	2+	2+	2+

(3+) severe; (2+) moderate; (+) mild; (neg) nil. IR-C: ischemia-reperfusion control; FEB10 + IR: febuxostat 10 mg/kg/day + ischemia-reperfusion; ALL100 + IR: allopurinol 100 mg/kg/day + ischemia-reperfusion.