Effect of Bioactive Compound of Aronia melanocarpa on Cardiovascular System in Experimental Hypertension

Table 3

Blood pressure (BP), relative heart weight (HW/BW), TNFα (pg/mL), and IL-6 level (pg/mL) of Wistar Kyoto rats treated with AME (57.90 mg/kg/day), with L-NAME (40 mg/kg/day), and with L-NAME (40 mg/kg/day) + AME (57.90 mg/kg/day) for 3 weeks and age-matched controls.

Group	BP (mmHg)	Hw/Bw (mg/g)	TNFα (pg/mL)	IL-6 (pg/mL)
WKY	118.39 ± 4.29	2.72 ± 0.05	12.11 ± 2.41	23.41 ± 3.78
WKY + AME	122.04 ± 1.81	2.55 ± 0.05	7.32 ± 2.12	22.14 ± 5.22
WKY + L-NAME	155.11 ± 3.71	2.95 ± 0.10	18.19 ± 1.38	36.43 ± 3.08
WKY + L-NAME + AME	129.22 ± 2.51	2.77 ± 0.02^#	13.89 ± 1.29^#	25.13 ± 2.11^#

Data are means ± SEM, significant differences: compared to age-matched controls; compared to L-NAME group.