|
| Sr. number | Combination polymer | Objective | Important findings | References |
|
| (1) | κ-Carrageenan | To examine the effect of FONPs on swelling, kinetics, and drug release mechanism. | Addition of MNPs causes high swelling ratio and forms stronger gels. The release rate of model drug can be tailored with the concentration of MNPs. | [70] |
| (2) | Poly vinyl alcohol | To control the release of drug (diclofenac sodium) via MNPs. | Drug release depends on pH and magnetic field. | [71] |
| (3) | Carboxymethyl chitosan | To modify drug release pattern. | Increase in drug release by applying external magnetic field as well as elevating of pH | [72] |
| (4) | Carrageenan | To enhance the performance of carrageenan hydrogels as drug delivery carrier in gastrointestinal conditions. | Less release of methylene blue in stomach. | [40] |
| (5) | κ-Carrageenan | To develop new nanocomposite hydrogels via in situ approach to find a suitable drug carrier for GIT release. | MB release increased with increased concentration of NPs. | [73, 74] |
| (6) | Poly(acrylic acid) | To produce novel biocompatible triple-response hydrogels based on k-CG. | Higher drug release in the absence of EMF at pH 7. | [75] |
| (7) | Calcium carbonate
(CaCO3) | To fabricate and characterize hybrid microparticles (hNPs) to deliver doxorubicin against cancer cells. | Coupling of λ-CG to folic acid increased the targeting of cancer cells. | [76] |
| (8) | Chitosan | To evaluate the release potential of natural polymer coated MNPs for controlled release of macromolecules. | Greater release of BSA at high pH. | [77] |
| (9) | None | To explore the synergistic effect of ι-CG and MNPs in drug delivery and cancer therapy. | Prepared nanocomposites proved to be potential candidate for cancer therapy due to apoptosis. | [78] |
| (10) | None | To explore the antibacterial applications of inorganic biodegradable hydrogels. | A strong zone of inhibition against Bacillus and Escherichia coli. | [79] |
| (11) | None | To formulate environment-friendly nanocomposite films comprising of carrageenan, AgNPs, and clay mineral to investigate their combined effect on antimicrobial activity and physicochemical film properties. | The combined use of both nanofillers (AgNPs and clay) showed potential antimicrobial activity against Gram-positive and Gram-negative bacteria. | [80] |
| (12) | None | To synthesize CG/CNF nanocomposite films and to study the effects of CNF concentrations on various properties of CG/CNF nanocomposite films. | Strong antimicrobial activity of the prepared films against Gram-positive food borne pathogens (Listeria monocytogenes). | [81] |
| (13) | None | To enhance the physical barrier and mechanical properties of CG based films by the addition of nanoclay as well as to check the antimicrobial effect of ZEO added in these films. | Strong microbial activity against S. aureus, B. cereus, E. coli, S. typhimurium, and P. aeruginosa. | [82] |
| (14) | Carbon nanotubes (CNTs) | To prepare CG-based hydrogels impregnated with CNTs and evaluate their swelling behavior and adsorption performance of crystal violet (CV) as model dye. | Lower adsorption of CV at acidic pHs and high adsorption at high pH. Moreover adsorption of CV also increases with increase in concentration of MCNT. | [83] |
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