Review Article

Roles and Mechanisms of Herbal Medicine for Diabetic Cardiomyopathy: Current Status and Perspective

Figure 2

Inflammation cascade in pathogenesis of DCM. AMPK: AMP activated-protein kinase; MAPK: mitogen-activated protein kinase; SIRT1: sirtuin 1; IKK: IκB kinase; RE: response element; PPAR: peroxisome proliferator-activated receptor; PGC1α: PPAR-γ co-activator-1; RXR: retinoid X receptor; PPRE: PPAR response elements; TNF-α: tumor necrosis factor-α; IL: interleukin.