Hydrogen-Rich Water Ameliorates Total Body Irradiation-Induced Hematopoietic Stem Cell Injury by Reducing Hydroxyl Radical

Figure 8

HW upregulates expression of NRF2 targeted proteins and enzyme activity of SOD2 and GPX1 in mice c-kit⁺ cells 15 days after 4 Gy TBI. (a) Bar graphs show the protein level of NRF2 in c-kit⁺ cells, as detected by FACS. (b) Representative FACS plots of NRF2. (c-d) Bar graphs show the protein level HO-1 and NQO1 in c-kit⁺ cells, as detected by FACS. (e-f) Bar graphs show the total enzyme activities of SOD and GPX in c-kit⁺ cells. All the data represent the mean ± SEM ( in panels (a), (c), and (d) and in panels (e)-(f)); versus 0 Gy control; versus 4 Gy control.

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