Modulation of Glutathione Hemostasis by Inhibition of 12/15-Lipoxygenase Prevents ROS-Mediated Cell Death after Hepatic Ischemia and Reperfusion

Figure 2

TUNEL assay of liver tissue (left posterior segment) exposed to ischemia-reperfusion injury. Representative images of TUNEL stainings demonstrating the differences in cell death after no/saline pretreatment (a), pretreatment with DMSO (b), and pretreatment with Baicalein (c). Quantitive planimetric analyses of TUNEL positive cells confirm a significant reduction of cell death after Baicalein pretreatment (Baicalein versus control by −64.8%, ; Baicalein versus vehicle DMSO by −54.1%, ) (d). Data are presented as the mean ± SEM.

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