PPAR-γ Activation Prevents Septic Cardiac Dysfunction via Inhibition of Apoptosis and Necroptosis

Figure 3

H&E staining of the myocardium and plasma levels of cardiotoxicity markers in septic rats. Myocardium and blood serum of rats subjected to CLP with or without pretreatment of rosiglitazone (ROT) or T007 were collected 18 hours after CLP. Myocardium architecture was visualized by (a) H&E staining. Cardiotoxicity was indicated by plasma levels of (b) cardiac injury marker, creatine kinase isoenzyme (CK-MB), and (c) necrosis marker, lactate dehydrogenase (LDH). versus sham. ^#, ^## versus CLP. Data are presented as mean ± SEM. per group.

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(b)

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