The Effects of Blast Exposure on Protein Deimination in the Brain

Figure 1

Protein deimination is catalyzed by a family of structurally related, calcium-dependent enzymes known as peptidylarginine deiminases (PADs). Protein deimination involves the conversion of an intraprotein arginine residue to a citrulline residue, resulting in the loss of a positively charged amine group and 1 Da in molecular mass.