The Effects of Blast Exposure on Protein Deimination in the Brain

Table 1

Mapping deimination sites in brain proteins of swine exposed to repeated mild blast exposure.

Protein	Peptide sequence	Observed mass	Charge state	Expected mass with neutral loss	Mass of peak detected
GABA transaminase	LVQQPQNVSTFINRPALGILPPENFVEK	1050.57	3	1036.24	1033.28
Aconitate hydratase	LNRPLTLSEK	391.23	3	376.89	376.67
Glial fibrillary acidic protein	ITIPVQTFSNLQIRETSLDTK	802.43	3	788.10	789.75
	TVEMRDGEVIK	647.32	2	625.82	625.82
Glutathione S-transferase	AFLASPEHVNRPINGNGK	481.25	4	470.50	469.23
Histone H4	ISGLIYEETRGVLKVFLENVIRDAVTYTEHAK	733.80	5	725.20	726.32
Vimentin	TVETRDGQVINETSQHHDDLE	808.70	3	794.37	794.37

R = deimination site.