ROS-Mediated Apoptosis and Genotoxicity Induced by Palladium Nanoparticles in Human Skin Malignant Melanoma Cells

<div>PdNPs induced apoptotic morphological changes. Fluorescence microphotograph of A375 cells showed apoptotic morphological changes in nanoparticle-treated cells: (a) control, (b) 20 <i>μ</i>g/ml, (c) 40 <i>μ</i>g/ml PdNP-treated cells, and (d) percentage apoptotic cells were calculated by scoring apoptotic (EtBr cells) and viable (AO cells) in 200 A375 cells. Values are given as means ± SE of triplicate experiments in each group. 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Arrow marks (→) represent the apoptotic indices.</div>

Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: ROS-Mediated Apoptosis and Genotoxicity Induced by Palladium Nanoparticles in Human Skin Malignant Melanoma Cells 