Research Article

ROS-Dependent Activation of Autophagy through the PI3K/Akt/mTOR Pathway Is Induced by Hydroxysafflor Yellow A-Sonodynamic Therapy in THP-1 Macrophages

Figure 7

Schematic diagram of the proposed mechanism underlying HSYA-SDT-induced autophagy and inflammation inhibition in THP-1 macrophages. HSYA-mediated SDT induces an autophagic response through the PI3K/Akt/mTOR signaling pathway mediated by ROS, thereby inhibiting inflammation.