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Oxidative Medicine and Cellular Longevity
Volume 2017, Article ID 8524353, 14 pages
Research Article

Mechanism of Mechanical Trauma-Induced Extracellular Matrix Remodeling of Fibroblasts in Association with Nrf2/ARE Signaling Suppression Mediating TGF-β1/Smad3 Signaling Inhibition

Department of Gynecology and Obstetrics, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China

Correspondence should be addressed to Li Hong; moc.liamg@7777ilgnohrd

Received 4 May 2017; Revised 29 July 2017; Accepted 9 August 2017; Published 3 October 2017

Academic Editor: Nageswara Madamanchi

Copyright © 2017 Jianming Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Material 1: Materials and methods. Supplementary Figures. Fig. S1: Validation of cell transfection. Fig. S2: Validation of Nrf2 knockout mice (Nfe2l2-/-). Supplementary Tables. Table S1: The body weights of mice in six groups (x¯±S).

  1. Supplementary Materials