Progression of Hepatic Adenoma to Carcinoma in Ogg1 Mutant Mice Induced by Phenobarbital

Figure 2

Formation of 8-OHdG and alterations to cell proliferation and apoptosis (ssDNA) in the livers of Ogg1^−/− and Ogg1^+/+ mice treated with PB at 500 ppm for 4 weeks (opened squares: control groups; black squares: PB-treated groups).

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