LC-QTOF-MS Analysis and Activity Profiles of Popular Antioxidant Dietary Supplements in Terms of Quality Control
Table 1
The declared ingredients of investigated dietary supplements.
Composition of the supplement (1 capsule/tablet)
Formulation
Recommended daily dose
Ingredients
Mass [mg]
S1 (turmeric)
Turmeric rhizome powder
720
Capsule
2
S2 (bilberry)
Powdered bilberry fruit
250
Tablet
2
Extract of bilberry including the following:
40
(i) Anthocyanins
10
(ii) Vit. C
40
(iii) Vit. E
6
(iv) Lutein
3
(v) Beta carotene
83.5
S3 (blend of extracts)
Extract from the root of Baikal skullcap
150
Capsule
2
Powdered cinnamon bark
60
Cranberry fruit extract
50
Extract from green tea leaves
50
Extract of the herb of horsetail
45
Vit. C
40
Extract of chokeberry
20
Extract from rhizomes of ginger
12
Extract of bilberry fruit
10
Extract of grape fruit
3
S4 (acai)
Extract of acai berry
300
Capsule
1
S5 (grapes)
Grape skin extract including
400
Capsule
1
(i) Trans-resveratrol
200
Grape seed extract including
100
(i) Proanthocyanidins
95
S6 (resveratrol)
Resveratrol (from an extract of Reynoutria japonica)
50
Capsule
1
S7 (Schisandra)
Powdered fruits of the Schisandra chinensis
525
Capsule
S8 (goji)
Extract of goji fruit including
300
Capsule
1
(i) Polysaccharides
150
S9 (pomegranate)
Pomegranate peel extract including
300
Capsule
1
(i) Elagic acid
120
S10 (spirulin)
Spirulin powder
450
Capsule
3–6
S11 (green tea)
55% green tea extract including the following:
250
Capsule
1-2
(i) EGCG (epigallocatechin gallate)
137.5
(ii) Polyphenols
249
(iii) Catechins
200
S12 (green coffee)
Extract of green coffee including the following:
800
Capsule
1
(i) Caffeine
34.8
(ii) Chlorogenic acid
400
S13 (hawthorn)
Powdered fruit of hawthorn
565
Capsule
1-2
S14 (OXXYNNEA and blend of extracts)
OXXYNNEA
200
Capsule
1
Grape seed extract (95% of proanthocyanidins)
150
Extract from green tea leaves (55% of EGCG)
150
Citrus bioflavonoids 40%
150
Trans-resveratrol
100
Extract of Rhodiola rosea root (4% of rosavins)
100
Quercetin
100
Extract from the leaves of artichoke (5% of cynarin)
50
Extract of cranberry fruit (10% of proanthocyanidins)
40
Alpha-lipoic acid
30
Coenzyme Q10
15
Astaxanthin
5
Lycopene
1
Beta carotene
1
S15 (green coffee)
An extract of green coffee beans (50% of chlorogenic acid) including
400
Capsule
2
(i) Caffeine
20
S16 (Ecklonia)
Ecklonia cava extract 25 : 1 (98.8% pure Ecklonia cava—the stem and leaves standardized to 15% polyphenols and phlorotannins)
53
Capsule
1
The fillers and additives forming capsule/tablet were omitted; OXXYNNEA—the blend of extracts of fruits and vegetables: white and red grapes, oranges, grapefruit, blueberry, papaya, pineapple, strawberries, apples, apricots, cherries, black currants, tomato, carrot, green tea, broccoli, cabbage, onions, garlic oil, wheat germ, cucumber, and asparagus.