Therapeutic Hypothermia Reduces Oxidative Damage and Alters Antioxidant Defenses after Cardiac Arrest

Figure 3

Antioxidant enzymatic activity at 6, 12, 36, and 72 h after cardiac arrest (CA) in normothermic () versus hypothermic () patients. In hypothermic patients, body temperature reached 33°C at 6 and 12 h and 36°C at 36 and 72 h after CA. (a) Superoxide dismutase (SOD) activity; (b) glutathione peroxidase (GPx) activity; (c) glutathione S-transferase (GST) activity; (d) paraoxonase-1 (PON1) activity. Data are expressed as mean ± standard error. Significantly different when comparing normothermic versus hypothermic groups at the same time point, .

(a) SOD activity

(b) GPx activity

(c) GST activity

(d) PON1 activity