Oxidative Medicine and Cellular Longevity / 2017 / Article / Fig 7

Research Article

Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress

Figure 7

Central corneal thickness of control (healthy) cornea and alkali-injured corneas treated with H2 dissolved in PBS (H2) or with PBS free of H2 (buffer) (a). Central corneal thickness was measured in the same rabbit before injury (day 0) and on days 2, 5, 10, and 20 after the injury. In buffer treated injured corneas and in H2 solution treated injured corneas the values for days 2 and 5 are statistically different (, ) from the values before injury. In H2 treated injured corneas the values for days 10 and 20 are not significantly different (n.s.) from values before injury. This is in contrast to buffer treated injured corneas, where the values for days 10 and 20 remain statistically different (, ) from values before injury. The quantification of corneal neovascularization is shown in (b). The number of vessels was high in buffer treated injured corneas and was significantly reduced in injured corneas treated with H2. The values with asterisks are significantly different () from values with buffer treated injured corneas.
(a)
(b)

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