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Oxidative Medicine and Cellular Longevity
Volume 2017 (2017), Article ID 9032792, 14 pages
https://doi.org/10.1155/2017/9032792
Research Article

Green Tea Polyphenols Ameliorate the Early Renal Damage Induced by a High-Fat Diet via Ketogenesis/SIRT3 Pathway

1Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
2MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
3Department of Nutrition and Food Hygiene, School of Public Health and Management, Binzhou Medical University, Yantai 264003, China
4Department of Hotel Management, Tourism University, Guilin 541000, China
5Department of Nutrition and Food Hygiene, Xinxiang Medical University, Xinxiang 453000, China
6Kecheng People’s Hospital, Quzhou 324000, China
7School of Nursing, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
8Department of Clinical Nutrition, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

Correspondence should be addressed to Xuezhi Zuo; nc.ude.umjt.hjt@7691ouZ and Chenjiang Ying; nc.ude.tsuh@jcgniy

Received 28 March 2017; Revised 12 May 2017; Accepted 25 May 2017; Published 26 July 2017

Academic Editor: Giuseppe Grosso

Copyright © 2017 Weijie Yi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Paoli, G. Bosco, E. M. Camporesi, and D. Mangar, “Ketosis, ketogenic diet and food intake control: a complex relationship,” Frontiers in Psychology, vol. 6, p. 27, 2015. View at Publisher · View at Google Scholar · View at Scopus
  2. M. P. Mattson, S. L. Chan, and W. Duan, “Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior,” Physiological Reviews, vol. 82, pp. 637–672, 2002. View at Publisher · View at Google Scholar
  3. J. M. Freeman, E. P. Vining, D. J. Pillas, P. L. Pyzik, and J. C. Casey, “The efficacy of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children,” Pediatrics, vol. 102, pp. 1358–1363, 1998. View at Publisher · View at Google Scholar
  4. D. G. Cotter, B. Ercal, X. Huang et al., “Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia,” The Journal of Clinical Investigation, vol. 124, pp. 5175–5190, 2014. View at Publisher · View at Google Scholar · View at Scopus
  5. T. Shimazu, M. D. Hirschey, J. Newman et al., “Suppression of oxidative stress by beta-hydroxybutyrate, an endogenous histone deacetylase inhibitor,” Science, vol. 339, pp. 211–214, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. M. M. Poplawski, J. W. Mastaitis, F. Isoda, F. Grosjean, F. Zheng, and C. V. Mobbs, “Reversal of diabetic nephropathy by a ketogenic diet,” PLoS One, vol. 6, article e18604, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. I. Kruljac, M. Cacic, P. Cacic et al., “Diabetic ketosis during hyperglycemic crisis is associated with decreased all-cause mortality in patients with type 2 diabetes mellitus,” Endocrine, vol. 55, pp. 139–143, 2017. View at Publisher · View at Google Scholar · View at Scopus
  8. A. Takagi, S. Kume, M. Kondo et al., “Mammalian autophagy is essential for hepatic and renal ketogenesis during starvation,” Scientific Reports, vol. 6, article 18944, 2016. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Avogaro, A. Valerio, L. Gnudi et al., “Ketone body metabolism in NIDDM. Effect of sulfonylurea treatment,” Diabetes, vol. 41, pp. 968–974, 1992. View at Publisher · View at Google Scholar
  10. N. Geidenstam, P. Spégel, H. Mulder, K. Filipsson, M. Ridderstråle, and A. P. Danielsson, “Metabolite profile deviations in an oral glucose tolerance test-a comparison between lean and obese individuals,” Obesity (Silver Spring), vol. 22, pp. 2388–2395, 2014. View at Publisher · View at Google Scholar · View at Scopus
  11. W. Yi, P. Fu, Z. Fan et al., “Mitochondrial HMG-CoA synthase partially contributes to antioxidant protection in the kidney of stroke-prone spontaneously hypertensive rats,” Nutrition, vol. 26, pp. 1176–1180, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Lin, T. T. Fung, F. B. Hu, and G. C. Curhan, “Association of dietary patterns with albuminuria and kidney function decline in older white women: a subgroup analysis from the Nurses’ Health Study,” American Journal of Kidney Diseases, vol. 57, pp. 245–254, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. S. J. Glastras, H. Chen, R. Teh et al., “Mouse models of diabetes, obesity and related kidney disease,” PLoS One, vol. 11, article e0162131, 2016. View at Publisher · View at Google Scholar · View at Scopus
  14. J. Zhang, H. Jiang, and J. Chen, “Combined effect of body mass index and metabolic status on the risk of prevalent and incident chronic kidney disease: a systematic review and meta-analysis,” Oncotarget, vol. 5, 2016. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Yang, X. Z. Zuo, C. Tian et al., “Green tea polyphenols attenuate high-fat diet-induced renal oxidative stress through SIRT3-dependent deacetylation,” Biomedical and Environmental Sciences, vol. 28, pp. 455–459, 2015. View at Publisher · View at Google Scholar · View at Scopus
  16. J. Yin, P. Han, Z. Tang, Q. Liu, and J. Shi, “Sirtuin 3 mediates neuroprotection of ketones against ischemic stroke,” Journal of Cerebral Blood Flow and Metabolism, vol. 35, pp. 1783–1789, 2015. View at Publisher · View at Google Scholar · View at Scopus
  17. T. Koyama, S. Kume, D. Koya et al., “SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells,” Free Radical Biology & Medicine, vol. 51, pp. 1258–1267, 2011. View at Publisher · View at Google Scholar · View at Scopus
  18. L. Tao, J. Y. Park, and J. D. Lambert, “Differential prooxidative effects of the green tea polyphenol, (-)-epigallocatechin-3-gallate, in normal and oral cancer cells are related to differences in sirtuin 3 signaling,” Molecular Nutrition & Food Research, vol. 59, pp. 203–211, 2015. View at Publisher · View at Google Scholar · View at Scopus
  19. A. Izquierdo-Lahuerta, C. Martinez-Garcia, and G. Medina-Gomez, “Lipotoxicity as a trigger factor of renal disease,” Journal of Nephrology, vol. 29, pp. 603–610, 2016. View at Publisher · View at Google Scholar · View at Scopus
  20. D. M. Small, J. S. Coombes, N. Bennett, D. W. Johnson, and G. C. Gobe, “Oxidative stress, anti-oxidant therapies and chronic kidney disease,” Nephrology (Carlton), vol. 17, pp. 311–321, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. M. Sohn, K. Kim, M. J. Uddin et al., “Delayed treatment with fenofibrate protects against high-fat diet-induced kidney injury in mice: the possible role of AMPK-autophagy,” American Journal of Physiology. Renal Physiology, vol. 312, 2017. View at Publisher · View at Google Scholar
  22. R. Aydi, A. B. Gara, R. Chaaben et al., “Hypolipidemic effect of dihydroisoquinoline oxaziridine in high-fat diet-fed rats,” Biomedicine & Pharmacotherapy, vol. 82, pp. 660–668, 2016. View at Publisher · View at Google Scholar · View at Scopus
  23. P. J. Ebenezer, N. Mariappan, C. M. Elks, M. Haque, and J. Francis, “Diet-induced renal changes in Zucker rats are ameliorated by the superoxide dismutase mimetic TEMPOL,” Obesity (Silver Spring), vol. 17, pp. 1994–2002, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. A. A. Elmarakby and J. D. Imig, “Obesity is the major contributor to vascular dysfunction and inflammation in high-fat diet hypertensive rats,” Clinical Science (London, England), vol. 118, pp. 291–301, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Wu, B. Gao, M. Li et al., “Hydrogen sulfide mitigates kidney injury in high fat diet-induced obese mice,” Oxidative Medicine and Cellular Longevity, vol. 2016, Article ID 2715718, 12 pages, 2016. View at Publisher · View at Google Scholar · View at Scopus
  26. T. Fiseha, “Urinary biomarkers for early diabetic nephropathy in type 2 diabetic patients,” Biomarker Research, vol. 3, p. 16, 2015. View at Publisher · View at Google Scholar
  27. H. S. Assal, S. Tawfeek, E. A. Rasheed, D. El-Lebedy, and E. H. Thabet, “Serum cystatin C and tubular urinary enzymes as biomarkers of renal dysfunction in type 2 diabetes mellitus,” Clinical Medicine Insights. Endocrinology and Diabetes, vol. 6, pp. 7–13, 2013. View at Publisher · View at Google Scholar · View at Scopus
  28. J. Segura, L. M. Ruilope, and J. L. Rodicio, “Microalbuminuria,” Clinical and Experimental Hypertension, vol. 26, pp. 701–707, 2004. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Maalouf, P. G. Sullivan, L. Davis, D. Y. Kim, and J. M. Rho, “Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation,” Neuroscience, vol. 145, pp. 256–264, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. M. Nagao, R. Toh, Y. Irino et al., “Beta-hydroxybutyrate elevation as a compensatory response against oxidative stress in cardiomyocytes,” Biochemical and Biophysical Research Communications, vol. 475, pp. 322–328, 2016. View at Publisher · View at Google Scholar · View at Scopus
  31. H. S. Noh, Y. S. Hah, R. Nilufar et al., “Acetoacetate protects neuronal cells from oxidative glutamate toxicity,” Journal of Neuroscience Research, vol. 83, pp. 702–709, 2006. View at Publisher · View at Google Scholar · View at Scopus
  32. Y. H. Youm, K. Y. Nguyen, R. W. Grant et al., “The ketone metabolite beta-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease,” Nature Medicine, vol. 21, pp. 263–269, 2015. View at Publisher · View at Google Scholar · View at Scopus
  33. H. R. Bae, D. H. Kim, M. H. Park et al., “Beta-hydroxybutyrate suppresses inflammasome formation by ameliorating endoplasmic reticulum stress via AMPK activation,” Oncotarget, vol. 7, pp. 66444–66454, 2016. View at Publisher · View at Google Scholar · View at Scopus
  34. R. D. Feinman, W. K. Pogozelski, A. Astrup et al., “Dietary carbohydrate restriction as the first approach in diabetes management: critical review and evidence base,” Nutrition, vol. 31, pp. 1–13, 2015. View at Publisher · View at Google Scholar · View at Scopus
  35. B. G. Allen, S. K. Bhatia, C. M. Anderson et al., “Ketogenic diets as an adjuvant cancer therapy: history and potential mechanism,” Redox Biology, vol. 2, pp. 963–970, 2014. View at Publisher · View at Google Scholar · View at Scopus
  36. A. K. Taggart, J. Kero, X. Gan et al., “(D)-beta-hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G,” The Journal of Biological Chemistry, vol. 280, pp. 26649–26652, 2005. View at Publisher · View at Google Scholar · View at Scopus
  37. P. F. Finn and J. F. Dice, “Ketone bodies stimulate chaperone-mediated autophagy,” The Journal of Biological Chemistry, vol. 280, pp. 25864–25870, 2005. View at Publisher · View at Google Scholar · View at Scopus
  38. M. T. Tran, Z. K. Zsengeller, A. H. Berg et al., “PGC1alpha drives NAD biosynthesis linking oxidative metabolism to renal protection,” Nature, vol. 531, pp. 528–532, 2016. View at Publisher · View at Google Scholar · View at Scopus
  39. N. E. Sunny, S. Satapati, X. Fu et al., “Progressive adaptation of hepatic ketogenesis in mice fed a high-fat diet,” American Journal of Physiology. Endocrinology and Metabolism, vol. 298, pp. E1226–E1235, 2010. View at Publisher · View at Google Scholar · View at Scopus
  40. M. D. Hirschey, T. Shimazu, J. A. Capra, K. S. Pollard, and E. Verdin, “SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2,” Aging (Albany New York), vol. 3, pp. 635–642, 2011. View at Publisher · View at Google Scholar
  41. T. Shimazu, M. D. Hirschey, L. Hua et al., “SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production,” Cell Metabolism, vol. 12, pp. 654–661, 2010. View at Publisher · View at Google Scholar · View at Scopus
  42. L. Perico, M. Morigi, and A. Benigni, “Mitochondrial sirtuin 3 and renal diseases,” Nephron, vol. 134, no. 1, pp. 14–19, 2016. View at Publisher · View at Google Scholar · View at Scopus
  43. D. B. Lombard, F. W. Alt, H. L. Cheng et al., “Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation,” Molecular and Cellular Biology, vol. 27, pp. 8807–8814, 2007. View at Publisher · View at Google Scholar · View at Scopus
  44. M. Morigi, L. Perico, C. Rota et al., “Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury,” The Journal of Clinical Investigation, vol. 125, pp. 715–726, 2015. View at Publisher · View at Google Scholar · View at Scopus
  45. M. Maalouf, J. M. Rho, and M. P. Mattson, “The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies,” Brain Research Reviews, vol. 59, pp. 293–315, 2009. View at Publisher · View at Google Scholar · View at Scopus
  46. X. Qiu, K. Brown, M. D. Hirschey, E. Verdin, and D. Chen, “Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation,” Cell Metabolism, vol. 12, pp. 662–667, 2010. View at Publisher · View at Google Scholar · View at Scopus
  47. R. Tao, M. C. Coleman, J. D. Pennington et al., “Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress,” Molecular Cell, vol. 40, pp. 893–904, 2010. View at Publisher · View at Google Scholar · View at Scopus
  48. N. R. Sundaresan, M. Gupta, G. Kim, S. B. Rajamohan, A. Isbatan, and M. P. Gupta, “Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice,” The Journal of Clinical Investigation, vol. 119, pp. 2758–2771, 2009. View at Publisher · View at Google Scholar · View at Scopus
  49. H. Yang, T. Yang, J. A. Baur et al., “Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival,” Cell, vol. 130, pp. 1095–1107, 2007. View at Publisher · View at Google Scholar · View at Scopus