Immune Profile of Obese People and In Vitro Effects of Red Grape Polyphenols on Peripheral Blood Mononuclear Cells

Figure 9

Release of proinflammatory cytokines in presence or absence of polyphenols. (a) IL-1β levels released from H and Ob PBMCs in presence or absence of 1, 3, and 5 μg dose polyphenols, respectively. (b) TNF-α levels released from H and Ob PBMCs in presence or absence of 1, 3, and 5 μg dose polyphenols, respectively. (c) IL-8 levels released from H and Ob PBMCs in presence or absence of 1, 3, and 5 μg dose polyphenols, respectively. (d) IL-6 levels released from H and Ob PBMCs in presence or absence of 1, 3, and 5 μg dose polyphenols, respectively. For abbreviations and statistical analysis, see Figure 1. (a) ° H unstimulated versus H 5 μg/ml, H 1 μg/ml versus H 5 μg/ml, ° H 3 μg/ml versus H 5 μg/ml, H 5 μg/ml versus Ob 5 μg/ml; (d) H 5 μg/ml versus Ob 5 μg/ml.

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