UPLC-MS/MS Profile of Alkaloids with Cytotoxic Properties of Selected Medicinal Plants of the Berberidaceae and Papaveraceae Families

Table 2

Analytical parameters of UPLC-MS/MS quantitative methods; data for calibration curves, limit of detection (LOD), and limit of quantification (LOQ) values for four analyzed alkaloids. , where is the peak area, is concentration of the alkaloids (μg/g), and R² is the correlation coefficient of the equation.

Analytes	Regression equations	R^2	Linear range (μg/g)	LOD (μg/g)	LOQ (μg/g)
Protopine		0.9992	88–2630	14.0	46.6
Berberine		0.9992	110–3316	47.8	159.6
Chelidonine		0.9996	122–3676	12.6	42.0
Sanguinarine		0.9997	106–3196	10.0	33.2