Cardiovascular Protective Effects of Salvianic Acid A on db/db Mice with Elevated Homocysteine Level

Table 2

Summary of echocardiography parameters.

Echocardiography parameters	DM (control)		DM (SAA)		DM (methionine)		DM (methionine + SAA)		Non-DM
	Baseline	Post	Baseline	Post	Baseline	Post	Baseline	Post	Baseline	Post
HR (bpm)	265.78 ± 14.22	249.93 ± 14.23	257.65 ± 12.47	263.32 ± 5.81	263.77 ± 14.00	241.28 ± 7.96	261.90 ± 9.85	238.63 ± 4.75	242.75 ± 6.53	242.26 ± 5.32
Morphological changes
LVIDd (mm)	3.79 ± 0.12	3.54 ± 0.20	3.96 ± 0.12	4.04 ± 0.11	3.80 ± 0.07	3.45 ± 0.22	3.90 ± 0.06	3.75 ± 0.10	3.70 ± 0.07	3.46 ± 0.78
LVIDs (mm)	2.08 ± 0.05	2.13 ± 0.16	2.34 ± 0.11	2.25 ± 0.11	2.03 ± 0.08	1.97 ± 0.22	2.15 ± 0.09	2.01 ± 0.10	2.16 ± 0.09	2.07 ± 0.09
PWd (mm)	0.53 ± 0.10	0.84 ± 0.09	0.49 ± 0.01	0.53 ± 0.02	0.55 ± 0.04	0.87 ± 0.10	0.56 ± 0.02	0.67 ± 0.05	0.57 ± 0.03	0.60 ± 0.02
PWs (mm)	0.79 ± 0.04	1.04 ± 0.08	0.80 ± 0.02	0.87 ± 0.03	0.83 ± 0.04	1.10 ± 0.09	0.94 ± 0.03	1.03 ± 0.06	0.87 ± 0.04	0.88 ± 0.03
IVSd (mm)	0.63 ± 0.06	0.87 ± 0.07	0.62 ± 0.02	0.58 ± 0.03	0.67 ± 0.02	0.84 ± 0.04	0.65 ± 0.04	0.65 ± 0.03	0.60 ± 0.02	0.65 ± 0.03
IVSs (mm)	1.08 ± 0.05	1.16 ± 0.09	1.06 ± 0.06	1.02 ± 0.05	1.02 ± 0.03	1.16 ± 0.07	1.02 ± 0.04	1.10 ± 0.05	0.96 ± 0.03	1.07 ± 0.04
LV mass (mg)	69.98 ± 2.54	104.29 ± 4.63	71.54 ± 2.27	73.63 ± 2.86	75.66 ± 2.40	99.64 ± 5.30	78.27 ± 2.07	81.65 ± 3.82	67.91 ± 2.07	65.74 ± 1.85
Functional changes
LV EF (%)	83.11 ± 1.29	78.02 ± 2.10	78.77 ± 2.00	82.33 ± 1.42	84.25 ± 1.50	80.68 ± 3.26	83.04 ± 1.35	84.10 ± 1.97	79.72 ± 1.72	78.04 ± 1.89
LV FS (%)	45.11 ± 1.45	40.08 ± 1.86	40.77 ± 2.03	44.30 ± 1.57	46.67 ± 1.71	44.34 ± 3.70	45.08 ± 1.49	46.53 ± 2.08	41.93 ± 1.83	40.23 ± 1.84

HR: heart rate; LVIDd: left ventricular internal dimensions (diastole); LVIDs: left ventricular internal dimensions (systole); PWd: posterior wall thicknesses (diastole); PWs: posterior wall thicknesses (systole); IVSd: interventricular septal thicknesses (diastole); IVSs: interventricular septal thicknesses (systole); EF: left ventricular ejection fraction; FS: left ventricular fractional shortening; LV mass: left ventricular mass. , , and when compared to its corresponding baseline values.