Research Article

Cardiovascular Protective Effects of Salvianic Acid A on db/db Mice with Elevated Homocysteine Level

Table 4

GSH, GSSG, and oxidative stress (GSH/GSSG ratio) in the liver tissue at the end of the experiment.

DM (control)DM (SAA)DM (methionine)DM (methionine + SAA)Non-DM

GSH (mg/g)3.04 ± 0.13a,c3.53 ± 0.17b3.06 ± 0.17a,c3.77 ± 0.104.28 ± 0.18
GSSG (mg/g)0.85 ± 0.170.62 ± 0.210.57 ± 0.060.78 ± 0.071.14 ± 0.12
Oxidative stress (GSH/GSSG ratio)4.05 ± 0.479.13 ± 2.245.60 ± 0.475.20 ± 0.584.11 ± 0.45

GSH: glutathione; GSSG: oxidized glutathione. a versus the non-DM group. b versus the non-DM group. c versus the DM (methionine + SAA) group. versus the non-DM group. versus the DM (SAA) group.