Research Article
Apoptotic Protease Activating Factor-1 Inhibitor Mitigates Myocardial Ischemia Injury via Disturbing Procaspase-9 Recruitment by Apaf-1
Table 1
Kinetics parameters for the binding of ZYZ-488 to Apaf-1.
| Concentrations (mM) | AbsResp (RU) | Slope (RU/s) | RelResp (RU) |
| 0 | 6744.9 | NO | 0 | 0.625 | 6747.1 | 0.02678 | 3.9 | 1.25 | 6749.7 | 0.03706 | 6.2 | 2.5 | 6754.2 | 0.02754 | 10.5 | 5 | 6762.9 | 0.03689 | 18.7 | 10 | 6780.2 | 0.06737 | 35.9 |
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