Research Article

Antiretroviral Therapy Initiation Alters the Redox System of Asymptomatic HIV-Infected Individuals: A Longitudinal Study

Table 1

Characterization of 30 PLWHA studied.

VariablesMEAN (±SD) or %
GeneralM0M1

Age (years)34 (±8.2)
Male gender60.0%
Smokers30.0%
Physical activities practice23.3%
Use of anxiolytics or antidepressants6.6%
Time since HIV diagnosis (years)2.2 (±3.2)
post-cART follow up period (months)8.1 (±1.4)
cART regimen: NRTI + NNRTI83.3%
cART regimen: NRTI + PI/r16.7%
CD4+ T nadir (cells/mL)335.7 (±211.3)
% of patients presenting CD4+ T <500 cells/mL70.0%86.6%
CD4+ T counts (cells/mL)454.69 (±136.4)625.07 (±276.9)
Undetectable HIV viral load3,3%80.0%

SD: standard deviation; PLWHA: people living with HIV/AIDS; cART: combined antiretroviral therapy; M0: before cART initiation; M1: after cART initiation; NRTI: nucleoside reverse-transcriptase inhibitors; NNRTI: nonnucleoside reverse-transcriptase inhibitors; PI/r: protease inhibitors reinforced with ritonavir; isolated presence of these cited factors (which were not excluded, due the adjustment of statistical analysis fulfilled). Statistical tests: Gamma Distribution and ANOVA, .