Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach

Figure 1

Profile of HPLC-UV and total ion current (TIC) chromatograms. (a) HPLC-UV chromatogram (10–30 min) of berberine, geniposide, and baicalin at 254 nm. (b) HPLC-UV chromatogram (10–30 min) of total extract of Huang-Lian-Jie-Du Decoction (HLJDD) at 254 nm. (c) Total ion current (TIC) chromatogram (10–48 min) of HLJDD extract analyzed by HPLC-QTOF-MS in a positive ion mode. Peaks 1–33 are listed in Supplementary Tables S–. (d) TIC chromatogram (10–48 min) of HLJDD analyzed by HPLC-QTOF-MS in a negative ion mode. Peaks 34–47 are listed in Supplementary Tables S and .

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