Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach

Figure 4

OPLS-DA based on ¹H NMR data from brain extracts of all groups. OPLS-DA score plots and the corresponding color-coded loading plots ((a) NC versus M, (b) HD versus M, (c) Ber versus M, (d) Bai versus M, and (e) Jas versus M) and S-plots (f) (). OPLS-DA scatter plots from brain extracts (g) of the statistical validations obtained by 2000 times permutation tests, with R² and Q² values in the vertical axis and the correlation coefficients (between the permuted and true class) in the horizontal axis, and OLS line representing the regression of R² and Q² on the correlation coefficients.

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