Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach

Figure 5

SUS-plot between HD and Ber (A), HD and Bai (B), and HD and Jas (C) of metabolites from serum (a) and the brain extracts (b). Metabolites (VIP > 1) in unique effects were found close to either the x- or y-axis for HD (red rectangle) and Ber/Bai/Jas (green rectangle), while the shared effects were located on the diagonals (metabolites close to the red diagonal line are positive correlation and those close to the green diagonal line are negative correlation). The shared and unique structures of metabolites were also visualized in Venn plots between HD and Ber (D), HD and Bai (E), and HD and Jas (F).

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