Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach

Figure 8

Effects of HLJDD and its three principal components on oxidative stress. (a) Boxplots for brain tissue levels of NO, MDA, CAT, Mn-SOD, Cu/Zn-SOD, GSH, GSSG, and GPx in each group (). The lines drawn at the bottom of each box, in the box, and at the top of the box represented the 1st, 2nd, and 3rd quartiles, respectively. The whiskers extended to ±1.5 times the interquartile range (from the 1st to 3rd quartile). All the data obtained were expressed as mean ± standard deviation (SD) (). ^## and ^###, MCAO group versus sham group; , , and , drug-treated groups versus MCAO group. (b) The protein level of NQO-1, Prx1, Prx3, Prx5, and Prx6 in brains treated with HLJDD and its three principals (). Results of quantitative analysis values are expressed as mean ± SD (). MCAO group versus sham group; , , and , drug-treated groups versus MCAO group. ns, no significant difference.

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