Thioredoxin-1 Protects Bone Marrow-Derived Mesenchymal Stromal Cells from Hyperoxia-Induced Injury In Vitro

<div>Effects of Trx-1 on intracellular ROS levels in BMSCs. (a) Intracellular ROS production was measured with CellROX deep red reagent, which can detect total ROS and was not the target particular species. The relative fluorescence intensity was expressed as % compared to control cells (BMSCs-p at 0 hr). (b) The level of intracellular H<sub>2</sub>O<sub>2</sub> was measured using hydrogen peroxide assay kit. 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BMSCs-p: empty lentivirus-engineered BMSCs; BMSCs-Trx-1: Trx-1-engineered BMSCs.</div>

Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Thioredoxin-1 Protects Bone Marrow-Derived Mesenchymal Stromal Cells from Hyperoxia-Induced Injury In Vitro 