Vialinin A, an Edible Mushroom-Derived p-Terphenyl Antioxidant, Prevents VEGF-Induced Neovascularization In Vitro and In Vivo

Figure 1

Effect of vialinin A on HUVEC proliferation. Growth-arrested HUVECs were pretreated with different concentrations of vialinin A (0 μM, 2.5 μM, 5 μM, and 10 μM) followed by treatment with VEGF (10 ng/mL) for (a) 24 h and (b) 48 h. MTT cell viability assay was performed as described in Materials and Methods. Values are the mean ± SD (). when compared to untreated control; ^# and ^## when compared to VEGF treated.

(a)

(b)