Reduced Levels of ATP Synthase Subunit ATP5F1A Correlate with Earlier-Onset Prostate Cancer

Figure 1

Staining of OXPHOS complexes, VDAC1, and AMACR/p63 in a prostate carcinoma of Gleason score 9 and adjacent benign prostate tissue. (a, b) NDUFS4; (c, d) SDHA; (e, f) UQCRC2; (g, h) MT-CO1; (i, j) ATP5F1A; (k, l) VDAC1; and (m, n) AMACR/p63. (a, c, e, g, i, k, m) carcinoma and (b, d, f, h, j, l, n) hyperplasia. The punches are 0.6 mm in diameter. AMACR/p63 staining was used to visualize carcinoma cells (brown) and benign prostate tissue (blue).

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