Research Article
Metabolic Syndrome Exacerbates the Recognition Memory Impairment and Oxidative-Inflammatory Response in Rats with an Intrahippocampal Injection of Amyloid Beta 1–42
Figure 2
Metabolic syndrome and Aβ1–42 injection in the hippocampus decrease the recognition memory in the novel object recognition test (NORt) in rats. Habituation phase (motor activity) and exploration time are not different in the vehicle (), Aβ1–42 (), MS (), and MS+ Aβ1–42 () groups (a, b). Several changes in the recognition index in the short-term recognition memory (STRM) and long-term memory (LTRM) can be observed in the MS and Aβ1–42 and their combination. The mean of each activity ± SE is plotted. Data were analyzed with one-way ANOVA and the posttest Bonferroni test (, , and compared with the vehicle group). compared with the MS group versus MS + Aβ1–42 groups.
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