Effects of Low-Frequency Electromagnetic Field on Oxidative Stress in Selected Structures of the Central Nervous System

Table 1

Concentrations of oxidative stress biomarkers: malondialdehyde (MDA) and total oxidant status (TOS); activity of antioxidant enzymes: superoxide dismutase (SOD) and isoenzymes (SOD-Mn, SOD-CuZn), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and glutathione S-transferase (GST); and concentration of nonenzymatic antioxidants—total antioxidant capacity (TAC) in the frontal cortex homogenates from rats exposed to low-frequency electromagnetic field (group A) and sham-exposed rats (control group) (group C) with results of ANOVA for all examined groups (A, C, M, and A + M) and post hoc NIR test for two selected groups: A and C.

	Group A	Group C	ANOVA results
Parameter			; value	value of NIR test
MDA concentration (μmol/g protein)	1.12 ± 0.09	1.04 ± 0.16	9.68; <0.001	0.538
TOS concentration (μmol/g protein)	2.17 ± 0.35	2.10 ± 0.39	0.6; 0.622	0.623
SOD activity (NU/mg protein)	49.38 ± 5.85	56.80 ± 3.25	13.02; <0.001	<0.001
SOD-Mn activity (NU/mg protein)	29.75 ± 3.12	35.05 ± 2.53	13.02; <0.001	<0.001
SOD-CuZn activity (NU/mg protein)	19.63 ± 4.45	21.75 ± 2.19	2.82; 0.040	0.219
CAT activity (IU/g protein)	6.16 ± 0.92	3.48 ± 1.05	17.66; <0.001	<0.001
GPx activity (IU/g protein)	0.59 ± 0.09	0.77 ± 0.13	3.87; 0.017	<0.01
GR activity (IU/g protein)	18.96 ± 1.98	19.91 ± 1.28	14.81; <0.001	0.097
GST activity (IU/g protein)	2.03 ± 0.21	2.99 ± 0.21	47.03; <0.001	<0.01
TAC concentration (mmol/g protein)	0.06 ± 0.00	0.07 ± 0.01	3.34; 0.031	<0.01