Effects of Low-Frequency Electromagnetic Field on Oxidative Stress in Selected Structures of the Central Nervous System

Table 2

Concentrations of oxidative stress biomarkers: malondialdehyde (MDA) and total oxidant status (TOS); activity of antioxidant enzymes: superoxide dismutase (SOD) and isoenzymes (SOD-Mn, SOD-CuZn), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and glutathione S-transferase (GST); and concentration of nonenzymatic antioxidants—total antioxidant capacity (TAC) in the hippocampus homogenates from rats exposed to low-frequency electromagnetic field (group A) and sham-exposed rats (control group) (group C) with results of ANOVA for all examined groups (A, C, M, and A + M) and post hoc NIR test for two selected groups: A and C.

	Group A	Group C	ANOVA results
Parameter			; value	value of NIR test
MDA concentration (μmol/g protein)	1.79 ± 0.48	1.56 ± 0.34	1.86; 0.156	0.294
TOS concentration (μmol/g protein)	2.68 ± 0.43	2.36 ± 0.23	1.50; 0.232	0.081
SOD activity (NU/mg protein)	70.73 ± 9.09	65.78 ± 6.63	8.78; 0.035	1.000
SOD-Mn activity (NU/mg protein)	38.75 ± 3.87	37.05 ± 3.02	13.66; <0.001	0.278
SOD-CuZn activity (NU/mg protein)	31.98 ± 6.64	28.73 ± 6.37	1.06; 0.379	0.212
CAT activity (IU/g protein)	5.02 ± 0.78	5.79 ± 0.76	14.40; <0.001	0.084
GPx activity (IU/g protein)	0.45 ± 0.19	0.47 ± 0.13	0.20; 0.898	0.848
GR activity (IU/g protein)	30.56 ± 3.34	26.97 ± 2.19	11.56; <0.001	<0.01
GST activity (IU/g protein)	3.92 ± 0.37	4.57 ± 0.28	6.96; <0.001	<0.01
TAC concentration (mmol/g protein)	0.10 ± 0.01	0.09 ± 0.01	0.38; 0.765	0.612