Effects of Low-Frequency Electromagnetic Field on Oxidative Stress in Selected Structures of the Central Nervous System

Table 4

Concentrations of oxidative stress biomarkers: malondialdehyde (MDA) and total oxidant status (TOS); activity of antioxidant enzymes: superoxide dismutase (SOD) and isoenzymes (SOD-Mn, SOD-CuZn), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and glutathione S-transferase (GST); and concentration of nonenzymatic antioxidants—total antioxidant capacity (TAC) in the hypothalamus homogenates from rats exposed to low-frequency electromagnetic field (group A) and sham-exposed rats (control group) (group C) with results of ANOVA for all examined groups (A, C, M, and A + M) and post hoc NIR test for two selected groups: A and C.

	Group A	Group C	ANOVA results
Parameter			; value	value of NIR test
MDA concentration (μmol/g protein)	1.03 ± 0.15	0.76 ± 0.13	11.76; <0.001	0.079
TOS concentration (μmol/g protein)	2.85 ± 0.51	2.68 ± 0.35	1.37; 0.268	0.535
SOD activity (NU/mg protein)	72.00 ± 12.56	82.99 ± 7.58	1.40; 0.260	0.064
SOD-Mn activity (NU/mg protein)	48.53 ± 5.67	52.41 ± 4.11	0.73; 0.543	0.263
SOD-CuZn activity (NU/mg protein)	23.46 ± 9.42	30.59 ± 3.76	6.48; 0.029	0.119
CAT activity (IU/g protein)	9.11 ± 2.78	8.80 ± 1.73	0.28; 0.841	0.800
GPx activity (IU/g protein)	0.47 ± 0.44	0.43 ± 0.30	0.54; 0.660	0.862
GR activity (IU/g protein)	23.91 ± 3.14	24.05 ± 2.22	2.69; 0.046	0.921
GST activity (IU/g protein)	4.86 ± 0.94	6.33 ± 0.49	11.18; <0.001	<0.001
TAC concentration (mmol/g protein)	0.09 ± 0.01	0.10 ± 0.01	1.03; 0.393	0.652