Effects of Low-Frequency Electromagnetic Field on Oxidative Stress in Selected Structures of the Central Nervous System

Table 6

Concentrations of oxidative stress biomarkers: malondialdehyde (MDA) and total oxidant status (TOS); activity of antioxidant enzymes: superoxide dismutase (SOD) and isoenzymes (SOD-Mn, SOD-CuZn), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and glutathione S-transferase (GST); and concentration of nonenzymatic antioxidants—total antioxidant capacity (TAC) in the cerebellum homogenates from rats exposed to low-frequency electromagnetic field (group A) and sham-exposed rats (control group) (group C) with results of ANOVA for all examined groups (A, C, M, and A + M) and post hoc NIR test for two selected groups: A and C.

	Group A	Group C	ANOVA results
Parameter			; value	value of NIR test
MDA concentration (μmol/g protein)	3.30 ± 1.269	2.76 ± 0.79	13.73; <0.001	0.292
TOS concentration (μmol/g protein)	4.14 ± 0.58	4.40 ± 0.76	14.82; <0.01	1.000
SOD activity (NU/mg protein)	99.80 ± 16.56	94.77 ± 4.84	21.23; <0.01	1.000
SOD-Mn activity (NU/mg protein)	97.71 ± 14.55	92.05 ± 4.12	20.89; <0.001	1.000
SOD-CuZn activity (NU/mg protein)	2.28 ± 2.17	2.71 ± 1.21	17.86; <0.001	1.000
CAT activity (IU/g protein)	12.38 ± 3.42	9.74 ± 2.96	4.07; 0.014	0.129
GPx activity (IU/g protein)	1.88 ± 0.23	1.79 ± 0.23	13.01; <0.01	1.000
GR activity (IU/g protein)	19.08 ± 3.36	18.93 ± 1.11	15.62; <0.01	1.000
GST activity (IU/g protein)	2.93 ± 0.42	3.58 ± 0.53	18.39; <0.001	<0.01
TAC concentration (mmol/g protein)	0.07 ± 0.06	0.13 ± 0.01	20.32; <0.001	1.000