Research Article

Lycium europaeum Extract: A New Potential Antioxidant Source against Cisplatin-Induced Liver and Kidney Injuries in Mice

Table 3

Effects of Lycium europaeum, quercetin, and cisplatin on the BW gain and liver and kidney index.

ParametersGroups
ControlLEMCisplatinLEM + cisplatinQuercetin + cisplatin

Initial BW (g)21.92 ± 0.6222.18 ± 0.1821.63 ± 0.3721.99 ± 0.4221.67 ± 0.34
Final BW (g)27.50 ± 1.2127.64 ± 0.6122.59 ± 0.2826.49 ± 0.925.89 ± 0.62
BW Gain (%)20.20 ± 3.0219.73 ± 1.244.27 ± 0.6516.86 ± 4.1216.21 ± 3.33
Liver weight (g)1.22 ± 0.011.25 ± 0.001.69 ± 0.011.50 ± 0.011.43 ± 0.03
Kidney weights (g)0.24 ± 0.020.26 ± 0.000.35 ± 0.020.28 ± 0.010.28 ± 0.01
Liver index (%)4.40 ± 0.144.52 ± 0.137.49 ± 0.045.65 ± 0.195.51 ± 0.07
Kidneys index (%)0.87 ± 0.060.98 ± 0.031.56 ± 0.101.07 ± 0.071.09 ± 0.08

Values represent mean ± SEM from three independent experiments, mice per group. Significant difference at and significant difference at : the cisplatin group versus the control group. Significant difference at and significant difference at : the LEM + cisplatin and quercetin + cisplatin groups versus the cisplatin group. Organ index (%) = (organ weight/body weight) × 100; LEM: Lycium europaeum methanol extract; BW: body weight.