Downregulated Expression of Solute Carrier Family 26 Member 6 in NRK-52E Cells Attenuates Oxalate-Induced Intracellular Oxidative Stress

Figure 3

Less Slc26a6 expression induced less oxalate crystal adhesion to cells and less intracellular vesicles. (a) Crystals were microscopically measured after a 24 h exposure. Red circle, one crystal. Magnification, ×100. (b) COM levels of cells. Data are (). . (c) After a 24 h oxalate treatment, ultrastructural observations using TEM. The micrographs showed that smaller intracellular vesicles were produced in NRK-siRNA. Yellow arrow indicates vesicles (TEM, ×5000).

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