Antiulcer Activity and Potential Mechanism of Action of the Leaves of Spondias mombin L.

Figure 10

Photomicrographs of gastric mucosa stained with H&E and PAS of the rats subjected to induction of chronic ulcer by 30% acetic acid. Animals were treated orally with 0.9% NaCl solution (LC: injured control), ranitidine (60 mg/kg), or ethanolic extract of the leaves of Spondias mombin (SmEE, 100 mg/kg) for 14 days. The filled arrow indicates the absence of the epithelial layer (ulcer area internal), and the dashed arrow indicates epithelial layer remaining (ulcer edge). Hematoxylin/eosin (H&E) and periodic acid-Schiff staining (PAS); magnification, 40x.