Antiulcer Activity and Potential Mechanism of Action of the Leaves of Spondias mombin L.

Figure 4

Histopathology of the gastric mucosa of rats of the experimental groups pretreated with 0.9% NaCl (injured control, a), lanzoprazole (30 mg/kg, b), and ethanolic extract of the leaves of Spondias mombin (SmEE 50, 100, and 200 mg/kg; c, d, and e, resp.) in ethanol-induced ulcer. Enlarged detail indicates the simple columnar epithelium of the pits. The arrows indicate gastric glands. The dashed arrows indicate congestion of blood capillaries. The asterisk () indicates edema of the lamina propria. The arrowhead (∆) indicates mononuclear inflammatory infiltrate diffuse. The dashed circles (◌) indicate gastric glands. Magnification, 100x.

(a)

(b)

(c)

(d)

(e)