Antiulcer Activity and Potential Mechanism of Action of the Leaves of Spondias mombin L.

Table 6

Effect of intraduodenal administration of ethanolic extract of the leaves of Spondias mombin (SmEE) on gastric secretion in Wistar rats subjected to pylorus ligature.

Treatment	pH	[H^+] (mEq/g/4 h)	Gastric content (g)
Noninjured	3.94 ± 0.39	4.43 ± 0.98	0.15 ± 0.03
Injured control	2.94 ± 0.33	12.19 ± 1.59	1.13 ± 0.19
SmEE (100 mg/kg)	3.50 ± 0.43	7.46 ± 0.85	0.82 ± 0.20
Ranitidine (60 mg/kg)	3.59 ± 0.38	6.61 ± 1.71	0.28 ± 0.06

The results are expressed as the mean ± SEM (n = 5–8/group). One-way ANOVA, followed by Dunnett’s multiple comparisons test; , , and .