Distribution of Paraoxonase-1 (PON-1) and Lipoprotein Phospholipase A2 (Lp-PLA2) across Lipoprotein Subclasses in Subjects with Type 2 Diabetes
Table 2
Lipid profile and distribution of lipoprotein subfractions in controls and T2DM subjects included in lipoprotein subsample.
T2DM ()
Controls ()
value
Total cholesterol (mg/dL)
188 ± 47
208 ± 32
<0.001
LDL-C (mg/dL)
114 ± 43
138 ± 30
<0.001
HDL-C (mg/dL)
34 ± 10
52 ± 9
<0.001
Triglycerides (mg/dL)
206 ± 91
88 ± 41
<0.001
HDL subfractions
Large HDL-C (%)
25 ± 7
33 ± 7
<0.001
Medium HDL-C (%)
47 ± 3
45 ± 4
0.001
Small HDL-C (%)
28 ± 6
21 ± 5
<0.001
Large HDL-C (mg/dL)
9 ± 4
18 ± 6
<0.001
Medium HDL-C (mg/dL)
16 ± 5
23 ± 4
<0.001
Small HDL-C (mg/dL)
9 ± 3
11 ± 3
<0.001
LDL subfractions
Large LDL-C (mg/dL)
51 ± 19
66 ± 20
<0.001
Small LDL-C (mg/dL)
17 ± 12
10 ± 10
<0.001
Mean LDL-C particle size (Å)
262 ± 5
268 ± 4
<0.01
IDL subfractions
Large IDL-C (mg/dL)
14 ± 5
12 ± 4
<0.001
Medium IDL-C (mg/dL)
15 ± 7
15 ± 6
0.200
Small IDL-C (mg/dL)
12 ± 6
17 ± 5
<0.001
VLDL-C (mg/dL)
45 ± 13
34 ± 8
<0.001
Data are expressed as means ± standard deviations. HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; VLDL-C: very low-density lipoprotein cholesterol; IDL-C: intermediate-density lipoprotein cholesterol.
